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Fibroblast Upregulation of Vitamin D Receptor Represents a Self-Protective Response to Limit Fibroblast Proliferation and Activation during Pulmonary Fibrosis

Dysregulation of vitamin D receptor (VDR) is implicated in chronic obstructive pulmonary disease. However, whether VDR dysregulation contributes to the development of pulmonary fibrosis remains largely unknown. Analysis of bulk and single-cell RNA profiling datasets revealed VDR upregulation in lung...

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Principais autores: Juan Wei, Junhui Zhan, Hui Ji, Yitong Xu, Qingfeng Xu, Xiaoyan Zhu, Yujian Liu
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI AG 2023-08-01
coleção:Antioxidants
Assuntos:
VDR
ER stress
JAK1
STAT3
fibroblast
pulmonary fibrosis
Acesso em linha:https://www.mdpi.com/2076-3921/12/8/1634
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