Mitochondrial-Targeted Triphenylphosphonium–Hydroxycamptothecin Conjugate and Its Nano-Formulations for Breast Cancer Therapy: In Vitro and In Vivo Investigation

Mitochondria are involved in various stages of cancer cell diffusion and metastasis. Therefore, targeting tumor mitochondria with antineoplastic medicines to cause mitochondria to initiate apoptosis may be an effective strategy for cancer therapy. Here, in order to enhance the anti-tumor efficacy of...

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Autori principali:	Kunfeng Zhang, Jingxin Fu, Xiaorui Liu, Yifei Guo, Meihua Han, Meifeng Liu, Xiangtao Wang
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	MDPI AG 2023-01-01
Serie:	Pharmaceutics
Soggetti:	mitochondrial targeting hydroxycamptothecin triphenylphosphine nanoparticles
Accesso online:	https://www.mdpi.com/1999-4923/15/2/388
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