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Mitochondrial-Targeted Triphenylphosphonium–Hydroxycamptothecin Conjugate and Its Nano-Formulations for Breast Cancer Therapy: In Vitro and In Vivo Investigation

Mitochondria are involved in various stages of cancer cell diffusion and metastasis. Therefore, targeting tumor mitochondria with antineoplastic medicines to cause mitochondria to initiate apoptosis may be an effective strategy for cancer therapy. Here, in order to enhance the anti-tumor efficacy of...

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Principais autores: Kunfeng Zhang, Jingxin Fu, Xiaorui Liu, Yifei Guo, Meihua Han, Meifeng Liu, Xiangtao Wang
Formato: Artigo
Idioma:Inglês
Publicado: MDPI AG 2023-01-01
Series:Pharmaceutics
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Acceso en liña:https://www.mdpi.com/1999-4923/15/2/388
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