Tunable protein synthesis by transcript isoforms in human cells

Eukaryotic genes generate multiple RNA transcript isoforms though alternative transcription, splicing, and polyadenylation. However, the relationship between human transcript diversity and protein production is complex as each isoform can be translated differently. We fractionated a polysome profile...

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Bibliographic Details

Main Authors:	Stephen N Floor, Jennifer A Doudna
Format:	Artigo
Language:	Inglês
Published:	eLife Sciences Publications Ltd 2016-01-01
Series:	eLife
Subjects:	transcript isoforms translational control deep sequencing engineered translation RNA processing RNA-seq
Online Access:	https://elifesciences.org/articles/10921
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