Single-Dose Intranasal or Intramuscular Administration of Simian Adenovirus-Based H1N1 Vaccine Induces a Robust Humoral Response and Complete Protection in Mice

Despite the widespread accessibility of vaccines and antivirals, seasonal influenza virus epidemics continue to pose a threat to public health. In this study, we constructed a recombinant replication-deficient simian adenovirus type 25 vector carrying the full-length hemagglutinin (HA) of the H1N1 i...

Ausführliche Beschreibung

Bibliografische Detailangaben

Hauptverfasser:	Daria V. Voronina, Irina V. Vavilova, Olga V. Zubkova, Tatiana A. Ozharovskaia, Olga Popova, Anastasia S. Chugunova, Polina P. Goldovskaya, Denis I. Zrelkin, Daria M. Savina, Irina A. Favorskaya, Dmitry V. Shcheblyakov, Denis Y. Logunov, Alexandr L. Gintsburg
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	MDPI AG 2025-08-01
Schriftenreihe:	Viruses
Schlagworte:	SAd25 ChAd68 adenoviral vector influenza H1N1 humoral immunity
Online-Zugang:	https://www.mdpi.com/1999-4915/17/8/1085
Tags:	Tag hinzufügen Keine Tags, Fügen Sie das erste Tag hinzu!