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Comparative analysis of rs12979860 SNP of the IFNL3 gene in children with hepatitis C and ethnic matched controls using 1000 Genomes Project data.

The rs12979860 single nucleotide polymorphism located on chromosome 19q13.13 near the interferon L3 gene (formerly and commonly known as interleukin 28B gene) has been associated in adults with both spontaneous and treatment induced clearance of hepatitis C virus. Although the exact mechanism of the...

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Autori principali: Giuseppe Indolfi, Giusi Mangone, Elisa Bartolini, Gabriella Nebbia, Pier Luigi Calvo, Maria Moriondo, Pier-Angelo Tovo, Maurizio de Martino, Chiara Azzari, Massimo Resti
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science (PLoS) 2014-01-01
Serie:PLoS ONE
Accesso online:https://doi.org/10.1371/journal.pone.0085899
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