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Dual Function of USP14 Deubiquitinase in Cellular Proteasomal Activity and Autophagic Flux

Summary: The ubiquitin-proteasome system and the autophagy-lysosome system are two major intracellular proteolytic pathways in eukaryotes. Although several biochemical mechanisms underlying the crosstalk between them have been suggested, little is known about the effect of enhanced proteasome activi...

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Autori principali: Eunkyoung Kim, Seoyoung Park, Jung Hoon Lee, Ji Young Mun, Won Hoon Choi, Yejin Yun, Jeeyoung Lee, Ji Hyeon Kim, Min-Ji Kang, Min Jae Lee
Natura: Artigo
Lingua:Inglês
Pubblicazione: Elsevier 2018-07-01
Serie:Cell Reports
Accesso online:http://www.sciencedirect.com/science/article/pii/S2211124718309859
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