Homocysteine-Mediated Neuronal Pyroptosis Contributes to Brain Injury in Heatstroke Rats by Activating the m⁶A-YTHDF2-NLRP3 Pathway

Heat stroke (HS) is a life-threatening condition that leads to neuronal injury, particularly in the prefrontal cortex, though its mechanisms remain unclear. In this study, we established a rat HS model and observed significant inflammatory responses and neuronal pyroptosis in the prefrontal cortex 6...

Ausführliche Beschreibung

Bibliografische Detailangaben

Hauptverfasser:	Shijia Zhang, Fang Xie, Xue Wang, Zhaowei Sun, Ling Zhang, Weiwei Liu, Xiaobing Chen, Lingjia Qian, Yun Zhao
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	MDPI AG 2025-09-01
Schriftenreihe:	Cells
Schlagworte:	heat stroke pyroptosis prefrontal cortex homocysteine NLRP3 PC12 cell line
Online-Zugang:	https://www.mdpi.com/2073-4409/14/18/1437
Tags:	Tag hinzufügen Keine Tags, Fügen Sie das erste Tag hinzu!