SPT6 loss permits the transdifferentiation of keratinocytes into an intestinal fate that resembles Barrett’s metaplasia
Summary: Transient depletion of the transcription elongation factor SPT6 in the keratinocyte has been recently shown to inhibit epidermal differentiation and stratification; instead, they transdifferentiate into a gut-like lineage. We show here that this phenomenon of transdifferentiation recapitula...
Guardat en:
| Autors principals: | , , , , , , |
|---|---|
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Elsevier
2021-10-01
|
| Col·lecció: | iScience |
| Matèries: | |
| Accés en línia: | http://www.sciencedirect.com/science/article/pii/S2589004221010890 |
| Etiquetes: |
Sense etiquetes, Sigues el primer a etiquetar aquest registre!
|