Breaking the ritual metabolic cycle in order to save acetyl CoA: A potential role for mitochondrial humanin in T2 bladder cancer aggressiveness

Introduction: Cancer cells may exhibit outsourcing of their high energy need in order to avoid the intrinsic mitochondrial apoptosis. Reduced mitochondrial respiration and accumulation of mitochondrial genome mutations are among metabolic transformations in this regard. Mitochondrial humanin (MT-RNR...

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Principais autores:	Nesreen Nabil Omar, Reham Fathy Tash, Youssef Shoukry, Karim Omar ElSaeed
Formato:	Artigo
Idioma:	Inglês
Publicado em:	SpringerOpen 2017-06-01
Colecção:	Journal of the Egyptian National Cancer Institute
Assuntos:	T2 bladder cancer Aerobic glycolysis Mitochondrial respiration MT-RNR2 MPC1
Acesso em linha:	http://www.sciencedirect.com/science/article/pii/S1110036217300286
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