AcuB senses cellular energy charge to coordinate acetyl-CoA synthesis in bacteria

Abstract Bacteria adjust their metabolism to the cellular energy state. AMP-forming acetyl-CoA-synthetase AcsA generates acetyl-CoA from acetate, ATP and CoA. In Bacilli, including Bacillus subtilis and Geobacillus stearothermophilus, AcsA is reversely transcribed upstream of the acu-operon encoding...

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Auteurs principaux:	Markus Janetzky, Norman Geist, Sabrina Schulze, Henriette Rückert, Kimani Gatzemeyer, Gottfried J. Palm, Leona Berndt, Britta Girbardt, Daniel Weis, Ina Menyes, Norma Welsch, Thomas Schweder, Mark Dörr, Stefan Kemnitz, Uwe T. Bornscheuer, Mihaela Delcea, Michael Lammers
Format:	Artigo
Langue:	Inglês
Publié:	Nature Portfolio 2026-04-01
Collection:	Nature Communications
Accès en ligne:	https://doi.org/10.1038/s41467-026-71006-w
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