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The mutual regulation of SOX12 and RNF168 modulates cisplatin resistance in esophageal squamous cell carcinoma cells by regulating DNA damage repair

Abstract Background Resistance to chemotherapy drugs is one of the significant factors for limited treatment options and poor prognosis in esophageal cancer. A study has found that SOX12 plays a role in cisplatin resistance in hepatocellular carcinoma cells, but the function and mechanism of SOX12 i...

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Autors principals: Ning Wang, Lun Yang, Yunhe Huang, Yanan Wang, Mingshan Liu, Jie Yang, Zhikai Zeng, Guobin Xie, Longhua Sun, Tianyu Han, Bentong Yu, Jiangbo Jin
Format: Artigo
Idioma:Inglês
Publicat: BMC 2026-01-01
Col·lecció:Cell & Bioscience
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Accés en línia:https://doi.org/10.1186/s13578-025-01505-8
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