K63-linked ubiquitylation of RMI1 by RNF8 is essential to its recruitment to stalled forks
Abstract RMI1 forms an evolutionarily conserved complex known as the BTR complex along with BLM and TOP3A. This complex plays a crucial role in DNA repair, particularly in the resolution of Holiday Junction like intermediates which are formed during homologous recombination. Despite the crucial role...
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| Principais autores: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Springer
2026-03-01
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| Colecção: | Cellular and Molecular Life Sciences |
| Assuntos: | |
| Acesso em linha: | https://doi.org/10.1007/s00018-026-06156-7 |
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