Role of Lactate Dehydrogenase in Tumor Metabolism and Progress of LDH-targeted Drugs
Abnormal energy metabolism is one of the main hallmarks of cancer. Studies have shown that tumor cells, even in the presence of oxygen, favored glycolysis to produce lactic acid and a small amount of ATP with the help of LDHA in the cytosol (the famous Warburg effect). The excessive lactate is then...
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| Format: | Artigo |
| Sprache: | Chinês |
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Magazine House of Cancer Research on Prevention and Treatment
2020-12-01
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| Schriftenreihe: | Zhongliu Fangzhi Yanjiu |
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| Online-Zugang: | http://html.rhhz.net/ZLFZYJ/html/8578.2020.20.0279.htm |
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