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Role of Lactate Dehydrogenase in Tumor Metabolism and Progress of LDH-targeted Drugs

Abnormal energy metabolism is one of the main hallmarks of cancer. Studies have shown that tumor cells, even in the presence of oxygen, favored glycolysis to produce lactic acid and a small amount of ATP with the help of LDHA in the cytosol (the famous Warburg effect). The excessive lactate is then...

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Principais autores: QIU Jinmei, GONG Juan, XIE Qingchi, XIE Zhizhong
Formato: Artigo
Idioma:Chinês
Publicado em: Magazine House of Cancer Research on Prevention and Treatment 2020-12-01
Colecção:Zhongliu Fangzhi Yanjiu
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Acesso em linha:http://html.rhhz.net/ZLFZYJ/html/8578.2020.20.0279.htm
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