Aspergillus niger is a superior expression host for the production of bioactive fungal cyclodepsipeptides

Abstract Background Fungal cyclodepsipeptides (CDPs) are non-ribosomally synthesized peptides produced by a variety of filamentous fungi and are of interest to the pharmaceutical industry due to their anticancer, antimicrobial and anthelmintic bioactivities. However, both chemical synthesis and isol...

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Autori principali:	Simon Boecker, Stefan Grätz, Dennis Kerwat, Lutz Adam, David Schirmer, Lennart Richter, Tabea Schütze, Daniel Petras, Roderich D. Süssmuth, Vera Meyer
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	BMC 2018-03-01
Serie:	Fungal Biology and Biotechnology
Soggetti:	Aspergillus niger Natural products Non-ribosomal peptide synthetase Tet-on Enniatin Beauvericin
Accesso online:	http://link.springer.com/article/10.1186/s40694-018-0048-3
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