TNF-α-Secreting Lung Tumor-Infiltrated Monocytes Play a Pivotal Role During Anti-PD-L1 Immunotherapy

Immune checkpoint blockade (ICB) of the PD-1 pathway revolutionized the survival forecast for advanced non-small cell lung cancer (NSCLC). Yet, the majority of PD-L1+ NSCLC patients are refractory to anti-PD-L1 therapy. Recent observations indicate a pivotal role for the PD-L1+ tumor-infiltrating my...

ver descrição completa

Detalhes bibliográficos

Principais autores:	Kirsten De Ridder, Hanne Locy, Elisa Piccioni, Miren Ibarra Zuazo, Robin Maximilian Awad, Stefaan Verhulst, Mathias Van Bulck, Yannick De Vlaeminck, Quentin Lecocq, Eva Reijmen, Wout De Mey, Lien De Beck, Thomas Ertveldt, Isabel Pintelon, Jean-Pierre Timmermans, David Escors, Marleen Keyaerts, Karine Breckpot, Cleo Goyvaerts
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Frontiers Media S.A. 2022-04-01
coleção:	Frontiers in Immunology
Assuntos:	anti-PD-L1 immunotherapy non small cell lung cancer (NSCLC) tumor-infiltrating myeloid cells TNF-α immunotherapy resistance
Acesso em linha:	https://www.frontiersin.org/articles/10.3389/fimmu.2022.811867/full
Tags:	Adicionar Tag Sem tags, seja o primeiro a adicionar uma tag!