Targeting MICA/B with cytotoxic therapeutic antibodies leads to tumor control [version 2; peer review: 2 approved]

Background: MICA and MICB are tightly regulated stress-induced proteins that trigger the immune system by binding to the activating receptor NKG2D on cytotoxic lymphocytes. MICA and MICB are highly polymorphic molecules with prevalent expression on several types of solid tumors and limited expressio...

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Үндсэн зохиолчид:	Mathieu Bléry, Manel Mrabet-Kraiem, Ariane Morel, Florence Lhospice, Delphine Bregeon, Cécile Bonnafous, Laurent Gauthier, Benjamin Rossi, Romain Remark, Stéphanie Cornen, Nadia Anceriz, Nicolas Viaud, Sylvia Trichard, Sabrina Carpentier, Alix Joulin-Giet, Gwendoline Grondin, Veronika Liptakova, Younghoon Kim, Laurent Daniel, Aurélie Haffner, Nicolas Macagno, Laurent Pouyet, Ivan Perrot, Carine Paturel, Yannis Morel, Alexander Steinle, François Romagné, Emilie Narni-Mancinelli, Eric Vivier
Формат:	Artigo
Хэл сонгох:	Inglês
Хэвлэсэн:	F1000 Research Ltd 2021-10-01
Цуврал:	Open Research Europe
Онлайн хандалт:	https://open-research-europe.ec.europa.eu/articles/1-107/v2
Шошгууд:	Шошго нэмэх Шошго байхгүй, Энэхүү баримтыг шошголох эхний хүн болох!