The Arp2/3 complex is required for in situ haptotactic response of microglia to iC3b
Abstract Microglia maintain brain homeostasis via iC3b-mediated synaptic pruning. The Arp2/3 complex has been implicated in iC3b-mediated macrophage phagocytosis, but it is unclear whether it is similarly required in microglia in the CNS. We examined the question of CR3-dependent clearance of iC3b i...
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| Hauptverfasser: | , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Springer Nature
2026-02-01
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| Schriftenreihe: | EMBO Reports |
| Schlagworte: | |
| Online-Zugang: | https://doi.org/10.1038/s44319-026-00720-9 |
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