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Treatment of microglia with Anti-PrP monoclonal antibodies induces neuronal apoptosis in vitro

Previous reports highlighted the neurotoxic effects caused by some motif-specific anti-PrPC antibodies in vivo and in vitro. In the current study, we investigated the detailed alterations of the proteome with liquid chromatography–mass spectrometry following direct application of anti-PrPC antibodie...

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Autors principals: Utpal Kumar Adhikari, Elif Sakiz, Umma Habiba, Meena Mikhael, Matteo Senesi, Monique Antoinette David, Gilles J. Guillemin, Lezanne Ooi, Tim Karl, Steven Collins, Mourad Tayebi
Format: Artigo
Idioma:Inglês
Publicat: Elsevier 2021-12-01
Col·lecció:Heliyon
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Accés en línia:http://www.sciencedirect.com/science/article/pii/S240584402102747X
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