Pharmacological Agents Targeting the Cellular Prion Protein
Prion diseases are associated with the conversion of the cellular prion protein (PrPC), a glycoprotein expressed at the surface of a wide variety of cell types, into a misfolded conformer (the scrapie form of PrP, or PrPSc) that accumulates in brain tissues of affected individuals. PrPSc is a self-c...
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| Principais autores: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
MDPI AG
2018-03-01
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| coleção: | Pathogens |
| Assuntos: | |
| Acesso em linha: | http://www.mdpi.com/2076-0817/7/1/27 |
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