LL-37 and citrullinated-LL-37 enhances oxylipins: citrullination attenuates LL-37-mediated COX-2-dependent chemokine response in human bronchial epithelial cells

Abstract Background During airway inflammation, chemokines, oxylipins (bioactive lipids) and cationic host defence peptides (CHDP) are enhanced in the lungs. However, the interplay of these molecules in the process of airway inflammation is not fully resolved. The human cathelicidin CHDP, LL-37, can...

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Κύριοι συγγραφείς:	Padmanie Ramotar, Mahadevappa Hemshekhar, Anthony Altieri, Anne M van der Does, Christopher D Pascoe, Neeloffer Mookherjee
Μορφή:	Artigo
Γλώσσα:	Inglês
Έκδοση:	BMC 2026-01-01
Σειρά:	Respiratory Research
Θέματα:	Cathelicidin LL-37 Lung Oxylipin COX-2 Airway inflammation
Διαθέσιμο Online:	https://doi.org/10.1186/s12931-026-03493-w
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