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A novel role of the PrpR as a transcription factor involved in the regulation of methylcitrate pathway in Mycobacterium tuberculosis.

Mycobacterium tuberculosis, the pathogen that causes tuberculosis, presumably utilizes fatty acids as a major carbon source during infection within the host. Metabolism of even-chain-length fatty acids yields acetyl-CoA, whereas metabolism of odd-chain-length fatty acids additionally yields propiony...

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Principais autores: Paweł Masiewicz, Anna Brzostek, Marcin Wolański, Jarosław Dziadek, Jolanta Zakrzewska-Czerwińska
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science (PLoS) 2012-01-01
coleção:PLoS ONE
Acesso em linha:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/22916289/pdf/?tool=EBI
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