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Molecular Dynamics of "Fuzzy" Transcriptional Activator-Coactivator Interactions.

Transcriptional activation domains (ADs) are generally thought to be intrinsically unstructured, but capable of adopting limited secondary structure upon interaction with a coactivator surface. The indeterminate nature of this interface made it hitherto difficult to study structure/function relation...

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Hlavní autoři: Natalie S Scholes, Robert O J Weinzierl
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science (PLoS) 2016-05-01
Edice:PLoS Computational Biology
On-line přístup:https://journals.plos.org/ploscompbiol/article/file?id=10.1371/journal.pcbi.1004935&type=printable
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