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Molecular Dynamics of "Fuzzy" Transcriptional Activator-Coactivator Interactions.

Transcriptional activation domains (ADs) are generally thought to be intrinsically unstructured, but capable of adopting limited secondary structure upon interaction with a coactivator surface. The indeterminate nature of this interface made it hitherto difficult to study structure/function relation...

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Bibliografiske detaljer
Principais autores: Natalie S Scholes, Robert O J Weinzierl
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science (PLoS) 2016-05-01
Serier:PLoS Computational Biology
Online adgang:https://journals.plos.org/ploscompbiol/article/file?id=10.1371/journal.pcbi.1004935&type=printable
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