Development of a polygenic risk score to improve screening for fracture risk: A genetic risk prediction study.

<h4>Background</h4>Since screening programs identify only a small proportion of the population as eligible for an intervention, genomic prediction of heritable risk factors could decrease the number needing to be screened by removing individuals at low genetic risk. We therefore tested whether a pol...

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Detalhes bibliográficos

Principais autores:	Vincenzo Forgetta, Julyan Keller-Baruch, Marie Forest, Audrey Durand, Sahir Bhatnagar, John P Kemp, Maria Nethander, Daniel Evans, John A Morris, Douglas P Kiel, Fernando Rivadeneira, Helena Johansson, Nicholas C Harvey, Dan Mellström, Magnus Karlsson, Cyrus Cooper, David M Evans, Robert Clarke, John A Kanis, Eric Orwoll, Eugene V McCloskey, Claes Ohlsson, Joelle Pineau, William D Leslie, Celia M T Greenwood, J Brent Richards
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Public Library of Science (PLoS) 2020-07-01
coleção:	PLoS Medicine
Acesso em linha:	https://doi.org/10.1371/journal.pmed.1003152
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