Addition of polygenic risk score to a risk calculator for prediction of breast cancer in US Black women

Abstract Background Previous work in European ancestry populations has shown that adding a polygenic risk score (PRS) to breast cancer risk prediction models based on epidemiologic factors results in better discriminatory performance as measured by the AUC (area under the curve). Following publicati...

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Bibliografski detalji

Glavni autori:	Gary R. Zirpoli, Ruth M. Pfeiffer, Kimberly A. Bertrand, Dezheng Huo, Kathryn L. Lunetta, Julie R. Palmer
Format:	Artigo
Jezik:	Inglês
Izdano:	BMC 2024-01-01
Serija:	Breast Cancer Research
Teme:	Risk prediction Breast cancer African American Polygenic risk score
Online pristup:	https://doi.org/10.1186/s13058-023-01748-8
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