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DNA repair and disease: insights from the human DNA glycosylase NEIL family

Abstract The base excision repair pathway protects DNA from base damage via oxidation, deamination, alkylation and methylation. DNA glycosylases are key enzymes that recognize damaged bases in a lesion-specific manner and initiate the base excision repair process. Among these, the endonuclease VIII-...

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Principais autores: Yuna Hwang, Su-Jin Kang, Jieun Kang, Jeongwoo Choi, Seung-Jin Kim, Sunbok Jang
Formato: Artigo
Idioma:Inglês
Publicado: Nature Publishing Group 2025-03-01
Series:Experimental and Molecular Medicine
Acceso en liña:https://doi.org/10.1038/s12276-025-01417-0
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