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Modeling extracellular matrix through histo-molecular gradient in NSCLC for clinical decisions

Lung cancer still represents a global health problem, being the main type of tumor responsible for cancer deaths. In this context, the tumor microenvironment, and the extracellular matrix (ECM) pose as extremely relevant. Thus, this study aimed to explore the prognostic value of epithelial-to-mesenc...

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Auteurs principaux: Camila Machado Baldavira, Tabatha Gutierrez Prieto, Juliana Machado-Rugolo, Jurandir Tomaz de Miranda, Lizandre Keren Ramos da Silveira, Ana Paula Pereira Velosa, Walcy Rosolia Teodoro, Alexandre Ab’Saber, Teresa Takagaki, Vera Luiza Capelozzi
Format: Artigo
Langue:Inglês
Publié: Frontiers Media S.A. 2022-11-01
Collection:Frontiers in Oncology
Sujets:
lung cancer
extracellular matrix
epithelial-to-mesenchymal transition
WNT signaling pathway
glycosaminoglycans
Accès en ligne:https://www.frontiersin.org/articles/10.3389/fonc.2022.1042766/full
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