Mesothelin expression remodeled the immune-matrix tumor microenvironment predicting the risk of death in patients with malignant pleural mesothelioma

BackgroundThe combination of immunobiological agents with immune checkpoint proteins is a promising treatment for malignant pleural mesothelioma (MPM). Mesothelin and anti-PD-L1 antibody-drug conjugates specifically target malignant neoplastic cells, inhibit the migration and invasion of neoplastic...

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Библиографические подробности

Главные авторы:	Aline Nery Qualiotto, Camila Machado Baldavira, Marcelo Balancin, Alexandre Ab’Saber, Teresa Takagaki, Vera Luiza Capelozzi
Формат:	Artigo
Язык:	Inglês
Опубликовано:	Frontiers Media S.A. 2023-10-01
Серии:	Frontiers in Immunology
Предметы:	malignant mesothelioma mesothelin PD-L1 immune cells computational quantification immunohistochemistry
Online-ссылка:	https://www.frontiersin.org/articles/10.3389/fimmu.2023.1268927/full
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