Fibril elongation by human islet amyloid polypeptide is the main event linking aggregation to membrane damage

The aggregation of human islet amyloid polypeptide (hIAPP) is linked to the death of pancreatic β-cells in type II diabetes. The process of fibril formation by hIAPP is thought to cause membrane damage, but the precise mechanisms are still unclear. Previously, we showed that the aggregation of hIAPP...

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Номзүйн дэлгэрэнгүй

Үндсэн зохиолчид:	Barend O.W. Elenbaas, Stefanie M. Kremsreiter, Lucie Khemtemourian, J. Antoinette Killian, Tessa Sinnige
Формат:	Artigo
Хэл сонгох:	Inglês
Хэвлэсэн:	Elsevier 2023-01-01
Цуврал:	BBA Advances
Нөхцлүүд:	Amyloid Protein aggregation Lipid vesicle Membrane biophysics Type 2 diabetes Islet amyloid polypeptide
Онлайн хандалт:	http://www.sciencedirect.com/science/article/pii/S2667160323000121
Шошгууд:	Шошго нэмэх Шошго байхгүй, Энэхүү баримтыг шошголох эхний хүн болох!