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Fibril elongation by human islet amyloid polypeptide is the main event linking aggregation to membrane damage

The aggregation of human islet amyloid polypeptide (hIAPP) is linked to the death of pancreatic β-cells in type II diabetes. The process of fibril formation by hIAPP is thought to cause membrane damage, but the precise mechanisms are still unclear. Previously, we showed that the aggregation of hIAPP...

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Ngā kaituhi matua: Barend O.W. Elenbaas, Stefanie M. Kremsreiter, Lucie Khemtemourian, J. Antoinette Killian, Tessa Sinnige
Hōputu: Artigo
Reo:Inglês
I whakaputaina: Elsevier 2023-01-01
Rangatū:BBA Advances
Ngā marau:
Urunga tuihono:http://www.sciencedirect.com/science/article/pii/S2667160323000121
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