Novel Approaches for the Solid-Phase Synthesis of Dihydroquinazoline-2(1<i>H</i>)-One Derivatives and Biological Evaluation as Potential Anticancer Agents

In the design of antineoplastic drugs, quinazolinone derivatives are often used as small molecule inhibitors for kinases or receptor kinases, such as the EGFR tyrosine kinase inhibitor gefitinib, p38MAP kinase inhibitor <b>DQO-501</b>, and BRD4 protein inhibitor <b>PFI-1</b>. A novel and convenient...

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Egile Nagusiak:	Qiong Wang, Ying Pan, Hongjun Luo, Yanmei Zhang, Fenfei Gao, Jinzhi Wang, Jinhong Zheng
Formatua:	Artigo
Hizkuntza:	Inglês
Argitaratua:	MDPI AG 2022-12-01
Saila:	Molecules
Gaiak:	solid-phase synthesis dihydroquinazoline-2(1<i>H</i>)-one anticancer antioxidation ADMET bioinformatics
Sarrera elektronikoa:	https://www.mdpi.com/1420-3049/27/23/8577
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