Novel Approaches for the Solid-Phase Synthesis of Dihydroquinazoline-2(1<i>H</i>)-One Derivatives and Biological Evaluation as Potential Anticancer Agents
In the design of antineoplastic drugs, quinazolinone derivatives are often used as small molecule inhibitors for kinases or receptor kinases, such as the EGFR tyrosine kinase inhibitor gefitinib, p38MAP kinase inhibitor <b>DQO-501</b>, and BRD4 protein inhibitor <b>PFI-1</b>. A novel and convenient...
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| Principais autores: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
MDPI AG
2022-12-01
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| coleção: | Molecules |
| Assuntos: | |
| Acesso em linha: | https://www.mdpi.com/1420-3049/27/23/8577 |
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