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Persistent Borna Disease Virus (BDV) infection activates microglia prior to a detectable loss of granule cells in the hippocampus

<p>Abstract</p> <p>Neonatal Borna Disease Virus (BDV) infection in rats leads to a neuronal loss in the cortex, hippocampus and cerebellum. Since BDV is a non-lytic infection <it>in vitro</it>, it has been suggested that activated microglia could contribute to neuronal damage. It is also conceivable...

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Príomhchruthaitheoirí: Vogel Michael W, Smith Kimberly, Moldovan Krisztina, Ovanesov Mikhail V, Pletnikov Mikhail V
Formáid: Artigo
Teanga:Inglês
Foilsithe / Cruthaithe: BMC 2008-05-01
Sraith:Journal of Neuroinflammation
Rochtain ar líne:http://www.jneuroinflammation.com/content/5/1/16
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