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Persistent Borna Disease Virus (BDV) infection activates microglia prior to a detectable loss of granule cells in the hippocampus

<p>Abstract</p> <p>Neonatal Borna Disease Virus (BDV) infection in rats leads to a neuronal loss in the cortex, hippocampus and cerebellum. Since BDV is a non-lytic infection <it>in vitro</it>, it has been suggested that activated microglia could contribute to neuronal damage. It is also conceivable...

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Bibliografische Detailangaben
Hauptverfasser: Vogel Michael W, Smith Kimberly, Moldovan Krisztina, Ovanesov Mikhail V, Pletnikov Mikhail V
Format: Artigo
Sprache:Inglês
Veröffentlicht: BMC 2008-05-01
Schriftenreihe:Journal of Neuroinflammation
Online-Zugang:http://www.jneuroinflammation.com/content/5/1/16
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