Netrin-1-UNC5B/neogenin axis enhances the stemness of colorectal cancer cells

Abstract Cancer stem cells were prominent responsible for cancer initiation, metastasis, and invasion as well as therapeutic resistance in colorectal cancer (CRC). The extracellular axon guidance factor netrin-1 has been found to be overexpressed in several malignant cancers such as glioma, lung can...

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Autors principals:	Xueli Xia, Zhenwei Mao, Wenxin Wang, Lin Zhao, Mengxue Xu, Jie Ma, Jie Tian, Kai Yin, Shengjun Wang
Format:	Artigo
Idioma:	Inglês
Publicat:	BMC 2025-11-01
Col·lecció:	Cell Communication and Signaling
Matèries:	Netrin-1 UNC5B Neogenin NF-κB ERK1/2 Cancer stemness
Accés en línia:	https://doi.org/10.1186/s12964-025-02489-1
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