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Navigator‐3, a modulator of cell migration, may act as a suppressor of breast cancer progression

Abstract Dissemination of primary tumor cells depends on migratory and invasive attributes. Here, we identify Navigator‐3 (NAV3), a gene frequently mutated or deleted in human tumors, as a regulator of epithelial migration and invasion. Following induction by growth factors, NAV3 localizes to the pl...

Ausführliche Beschreibung

Gespeichert in:
Hauptverfasser: Hadas Cohen‐Dvashi, Nir Ben‐Chetrit, Roslin Russell, Silvia Carvalho, Mattia Lauriola, Sophia Nisani, Maicol Mancini, Nishanth Nataraj, Merav Kedmi, Lee Roth, Wolfgang Köstler, Amit Zeisel, Assif Yitzhaky, Jacques Zylberg, Gabi Tarcic, Raya Eilam, Yoav Wigelman, Rainer Will, Sara Lavi, Ziv Porat, Stefan Wiemann, Sara Ricardo, Fernando Schmitt, Carlos Caldas, Yosef Yarden
Format: Artigo
Sprache:Inglês
Veröffentlicht: Springer Nature 2015-02-01
Schriftenreihe:EMBO Molecular Medicine
Schlagworte:
cancer
cell migration
cytoskeleton
growth factor
microtubules
Online-Zugang:https://doi.org/10.15252/emmm.201404134
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