Comparison of Mesenchymal Stromal Cells From Different Origins for the Treatment of Graft-vs.-Host-Disease in a Humanized Mouse Model

Mesenchymal stromal cells (MSCs) have potent immunomodulatory properties that make them an attractive tool against graft- vs.-host disease (GVHD). However, despite promising results in phase I/II studies, bone marrow (BM-) derived MSCs failed to demonstrate their superiority over placebo in the sole...

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Autors principals:	Céline Grégoire, Caroline Ritacco, Muriel Hannon, Laurence Seidel, Loïc Delens, Ludovic Belle, Sophie Dubois, Sophie Vériter, Chantal Lechanteur, Alexandra Briquet, Sophie Servais, Gregory Ehx, Yves Beguin, Frédéric Baron
Format:	Artigo
Idioma:	Inglês
Publicat:	Frontiers Media S.A. 2019-04-01
Col·lecció:	Frontiers in Immunology
Matèries:	mesenchymal stromal cells graft-vs.-host-disease hematopoietic stem cell transplantation xenogeneic NSG bone marrow
Accés en línia:	https://www.frontiersin.org/article/10.3389/fimmu.2019.00619/full
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