Nanobody-based pannexin1 channel inhibitors reduce inflammation in acute liver injury

Abstract Background The opening of pannexin1 channels is considered as a key event in inflammation. Pannexin1 channel-mediated release of adenosine triphosphate triggers inflammasome signaling and activation of immune cells. By doing so, pannexin1 channels play an important role in several inflammat...

Celý popis

Podrobná bibliografie

Hlavní autoři:	Raf Van Campenhout, Timo W. M. De Groof, Prashant Kadam, Brenda R. Kwak, Serge Muyldermans, Nick Devoogdt, Mathieu Vinken
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	BMC 2023-10-01
Edice:	Journal of Nanobiotechnology
Témata:	Acute liver disease Inflammation Nanobody Pannexin1 Therapy
On-line přístup:	https://doi.org/10.1186/s12951-023-02137-1
Tagy:	Přidat tag Žádné tagy, Buďte první, kdo vytvoří štítek k tomuto záznamu!