Nanobody-based pannexin1 channel inhibitors reduce inflammation in acute liver injury
Abstract Background The opening of pannexin1 channels is considered as a key event in inflammation. Pannexin1 channel-mediated release of adenosine triphosphate triggers inflammasome signaling and activation of immune cells. By doing so, pannexin1 channels play an important role in several inflammat...
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| Autores principales: | , , , , , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
BMC
2023-10-01
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| Colección: | Journal of Nanobiotechnology |
| Materias: | |
| Acceso en línea: | https://doi.org/10.1186/s12951-023-02137-1 |
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