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Lactylation modification regulates acute myeloid leukemia pathogenesis and immune microenvironment

Abstract Background Acute myeloid leukemia (AML) is a complex hematological malignancy with high mortality, particularly in the elderly. Current treatments, including chemotherapy, targeted therapies, and emerging immunotherapies such as T cell engager (TCE) and CAR-T, face challenges such as drug r...

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Bibliographic Details
Main Authors: Ruixue Dai, Guodong Sui
Format: Artigo
Language:Inglês
Published: Springer 2025-11-01
Series:Discover Oncology
Subjects:
Online Access:https://doi.org/10.1007/s12672-025-03979-x
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