Appraising the causal relationship between thyroid function and rheumatoid arthritis: a two-sample bidirectional Mendelian randomization study

BackgroundHypothyroidism and hyperthyroidism are observationally associated with rheumatoid arthritis (RA), but causality is unclear. To evaluate the causal relationship between thyroid function and RA, we conducted a two-Sample bidirectional Mendelian Randomization (MR) study.MethodsSingle nucleoti...

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Autori principali:	Peng Gu, Bin Pu, YangCheng Ma, Dan Yue, Qiao Xin, HaiShan Li, Teng Liu, XiaoHui Zheng, ChongZhi Ouyang
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	Frontiers Media S.A. 2023-11-01
Serie:	Frontiers in Immunology
Soggetti:	Mendelian randomization rheumatoid arthritis hyperthyroidism hypothyroidism free thyroxine thyroid-stimulating hormone
Accesso online:	https://www.frontiersin.org/articles/10.3389/fimmu.2023.1238757/full
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