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Appraising the causal relationship between thyroid function and rheumatoid arthritis: a two-sample bidirectional Mendelian randomization study

BackgroundHypothyroidism and hyperthyroidism are observationally associated with rheumatoid arthritis (RA), but causality is unclear. To evaluate the causal relationship between thyroid function and RA, we conducted a two-Sample bidirectional Mendelian Randomization (MR) study.MethodsSingle nucleoti...

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Principais autores: Peng Gu, Bin Pu, YangCheng Ma, Dan Yue, Qiao Xin, HaiShan Li, Teng Liu, XiaoHui Zheng, ChongZhi Ouyang
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2023-11-01
Serier:Frontiers in Immunology
Fag:
Mendelian randomization
rheumatoid arthritis
hyperthyroidism
hypothyroidism
free thyroxine
thyroid-stimulating hormone
Online adgang:https://www.frontiersin.org/articles/10.3389/fimmu.2023.1238757/full
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