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Autologous induced pluripotent stem cell-derived four-organ-chip

Microphysiological systems play a pivotal role in progressing toward a global paradigm shift in drug development. Here, we designed a four-organ-chip interconnecting miniaturized human intestine, liver, brain and kidney equivalents. All four organ models were predifferentiated from induced pluripote...

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Glavni autori: Anja Patricia Ramme, Leopold Koenig, Tobias Hasenberg, Christine Schwenk, Corinna Magauer, Daniel Faust, Alexandra K Lorenz, Anna-Catharina Krebs, Christopher Drewell, Kerstin Schirrmann, Alexandra Vladetic, Grace-Chiaen Lin, Stephan Pabinger, Winfried Neuhaus, Frederic Bois, Roland Lauster, Uwe Marx, Eva-Maria Dehne
Format: Artigo
Jezik:Inglês
Izdano: Taylor & Francis Group 2019-09-01
Serija:Future Science OA
Teme:
differentiation
four-organ-chip
induced pluripotent stem cells
microphysiological system
multi-organ-chip
Online pristup:https://www.future-science.com/doi/10.2144/fsoa-2019-0065
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