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Usefulness of a humanized tricellular static transwell blood–brain barrier model as a microphysiological system for drug development applications. - A case study based on the benchmark evaluations of blood-brain barrier microphysiological system

Microphysiological system (MPS), a new technology for in vitro testing platforms, have been acknowledged as a strong tool for drug development. In the central nervous system (CNS), the blood‒brain barrier (BBB) limits the permeation of circulating substances from the blood vessels to the brain, ther...

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Autors principals: Kimiko Nakayama-Kitamura, Yukari Shigemoto-Mogami, Hiroko Toyoda, Ikue Mihara, Hiroyuki Moriguchi, Hitoshi Naraoka, Tomomi Furihata, Seiichi Ishida, Kaoru Sato
Format: Artigo
Idioma:Inglês
Publicat: Elsevier 2023-03-01
Col·lecció:Regenerative Therapy
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Accés en línia:http://www.sciencedirect.com/science/article/pii/S2352320423000111
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