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The expression of BHLHE22 in endometrial carcinoma: Associations with mismatch repair protein expression status, tumor-infiltrating immune cells, programmed death-ligand 1 and clinical outcomes

Objective: Endometrial cancer (EC) shows substantial heterogeneity in their immune microenvironment. BHLHE22 is consistently hypermethylated in EC and high expression of BHLHE22 is likely to be immunosuppressive in the tumor microenvironment. Herein, we evaluated expression of BHLHE22, programmed ce...

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Principais autores: Lin-Yu Chen, Hsing-Yu Chen, Hung-Cheng Lai, Shiou-Fu Lin, Kuo-Chang Wen, Darmawi, Phui-Ly Liew
Format: Artigo
Sprog:Inglês
Udgivet: Elsevier 2025-01-01
Serier:Taiwanese Journal of Obstetrics & Gynecology
Fag:
BHLHE22
Endometrial cancer
PD-L1
Survival
Tumor-infiltrating immune cells
Online adgang:http://www.sciencedirect.com/science/article/pii/S1028455924002857
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