M6a-Bhlhe22 Modulates Pi3k/Akt In Osteoporotic Bmsc Osteogenesis

Aim or purpose: This study elucidates the novel role of m6A-modified BHLHE22 in impairing BMSC osteogenesis via PI3K/AKT dysregulation, offering a potential epigenetic target for osteoporosis therapy (Zhang et al., Nat Commun 2023;14:1234-1245). Materials and methods: Ovariectomized (OVX) SD rats (n...

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Detalles Bibliográficos

Principais autores:	Qiaonan Ye, Jingang Xiao, Qianke Tao, Xuemei Long
Formato:	Artigo
Idioma:	Inglês
Publicado:	Elsevier 2025-10-01
Series:	International Dental Journal
Assuntos:	m6A methylation BHLHE22 PI3K/AKT signaling pathway Osteoporosis Osteogenic differentiation
Acceso en liña:	http://www.sciencedirect.com/science/article/pii/S0020653925050610
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