Clinical profile, atrophy and inheritance patterns of pathogenic MAPT gene mutations in Frontotemporal dementia detected using whole exome sequencing: a single-center first report from India

Abstract Background/Objectives Frontotemporal Dementia (FTD) is one of the common causes of early-onset degenerative dementia and is a clinically and pathologically heterogeneous group of neurodegenerative disorders. Globally, Microtubule Associated Protein Tau (MAPT), progranulin (GRN), and Chromos...

Cur síos iomlán

Sonraí bibleagrafaíochta

Príomhchruthaitheoirí:	Subasree Ramakrishnan, Faheem Arshad, B. S. Keerthana, Susan Bosco, Arun Gokul Pon, V. H. Ganaraja, Deekshitha Madhusudhan, R. Mahima, Gautham Arunachal, Karthick Kulanthaivelu, Suvarna Alladi
Formáid:	Artigo
Teanga:	Inglês
Foilsithe / Cruthaithe:	BMC 2025-08-01
Sraith:	BMC Neurology
Ábhair:	Frontotemporal dementia MAPT GRN SQSTM1 Whole Exome Sequencing
Rochtain ar líne:	https://doi.org/10.1186/s12883-025-04336-9
Clibeanna:	Cuir clib leis Níl clibeanna ann, Bí ar an gcéad duine le clib a chur leis an taifead seo!