Advances in Small-Molecule C-KIT/PDGFRα Inhibitors for the Treatment of Gastrointestinal Stromal Tumors
Stem cell factor receptor (C-KIT) or platelet-derived growth factor receptor α (PDGFRα) gene mutations have been identified as oncogenic drivers for most gastrointestinal stromal tumors (GISTs). Thus, small-molecule inhibitors of C-KIT or PDGFRα have emerged as effective treatments for GISTs. Althou...
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| Auteurs principaux: | , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Georg Thieme Verlag KG
2024-12-01
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| Collection: | Pharmaceutical Fronts |
| Sujets: | |
| Accès en ligne: | http://www.thieme-connect.de/DOI/DOI?10.1055/s-0044-1791541 |
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